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Posts Tagged ‘polyphenol’

What Makes Wine, Wine

Monday, June 13th, 2011

Chances are, the last time you enjoyed a glass of red wine, that you gave much thought to why the wine looked, smelled and tasted as it did.  Unless you’re steeped in the biochemistry field, you (and I) are simply searching for that well balanced red that can be enjoyed on its own or with food.  But have you ever given thought to why a red looks, smells, tastes and “feels” the way it does in your mouth?  What is it that makes it the perfect match for food or alternatively, what is it that simply fights with a dish? The answer lies within the field of biochemistry.

If not already, familiarize yourself with the term phenol.  While I have no intention of launching into a detailed discussion about the chemical structure of this group of several hundred compounds, they all have a common structural element, a hydroxyl group (-OH) bonded directly to an aromatic hydrocarbon group.  But oh yes, I promised that I would steer clear of biochemistry.  Anyway, bond more than one phenol together and you get……….polyphenols.

Polyphenols are commonly divided into two sub-categories:  flavinoids and non-flavinoids.  As the name implies, flavinoids contain compounds that contribute color and mouthfeel of the wine such as anthocyanins and tannins while the non-flavinoids include the highly publicized and touted compound Resveratrol and numerous acids.

Resveratrol Demonstrates Anti-Viral Properties

Monday, October 19th, 2009

A study in the July edition of the Journal of Experimental and Clinical Cancer Research hints that Resveratrol, the polyphenol, antioxidant 800 pound gorilla, may be capable of inhibiting viral replication at the cellular level.  The study was conducted at the Sapienza University in Rome.  Co-author Gianfranco Risuleo, said that viral DNA replication seems to be inhibited in the nucleus of the cell.

Two groups of mouse tissue, one with tumors and the other without, were exposed to a particular virus and subsequently to either 20 or 40 micromoles of resveratrol.  For comparison, a control group was not exposed to any resveratrol.

Resveratrol, Compound du Jour: Facts and Fiction

Thursday, September 24th, 2009

Resveratrol, it seems, just can’t seem to catch its breath.  Whether the focus of still another research study on its potential health benefits (see archived articles: Wine and Inflammation, Radioprotective Effects of Wine, Alcohol Impact on Alzheimer’s in the Elderly, Wine Consumption in Males May Extend Life, Grape Seed Extracts May Suppress Leukemic Cells, Study Finds Heightened Risk of Breast Cancer With Wine, Resveratrol May Counteract Obesity and Resveratrol May Limit Damage Post Stroke) or advertised as a “cure all for what ails ya,” word of the compound seems to be everywhere.  So what is resveratrol?

Resveratrol is what is known as a polyphenol found in, amongst other things, the skin of red grapes.  Phenolic compounds, a type of antioxidant, are divided into flavinoids (those compounds that are responsible for the flavor and taste of grapes and other fruits such as tannins) and non flavinoids, of which resveratrol is a member.  Resveratrol is also found in peanuts, mulberries, blueberries, cranberries, spruce, eucalyptus and various Chinese herbs.  Now that I have bored you with some very basic chemistry, lets get into the facts. 

Resveratrol May Limit Damage Post Stroke:

Monday, December 29th, 2008
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